Companies: 10,795·Total market cap: $144.5T
Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated

VRTXNASDAQHealthcare● Active
$446.83
+$5.09(+1.15%)
Market Cap$113.4B
P/E Ratio
52W High$507.92
52W Low$362.5

Vertex Pharmaceuticals Incorporated (VRTX) PE Ratio — Current & Historical Data

Trailing twelve months (TTM) P/E, forward P/E, PEG, and annual PE history — from market prices and filings.

vrtx · pe ratio · data through Dec 31, 2025

Core PE Ratio Metrics

Trailing 12 months · TTM

The price-to-earnings (P/E) ratio for Vertex Pharmaceuticals Incorporated (VRTX) measures how much investors pay for each dollar of the company's trailing earnings. VRTX's current PE ratio of 26.17x is calculated by dividing its stock price of $446.83 by its TTM earnings per share of $17.07. +2.8% elevated vs 5Y avg 25.5x

26.17x
P/E Ratio (TTM)+2.8%

Source: FMP · /ratios-ttm · /analyst-estimates · 2025-12-31

Forward P/E
20.67x
FY2027 est. EPS $21.62
Based on 18 analysts
EPS (TTM)
$17.07
TTM · diluted EPS
PEG Ratio
0.04
Below 1.0 · Growth adjusted
Source: FMP · /ratios-ttm · /ratios annual · /analyst-estimates · /stock-peers · Vertex Pharmaceuticals Incorporated SEC 10-K & 10-Q filings · US GAAPUpdated: 2026-06-08

PE Ratio History

2006 – 2025 · Annual
PE Ratio (TTM)
5Y Avg 25.5x
EPS (Annual)

▸ FMP /ratios?period=annual&limit=20 · priceToEarningsRatio + netIncomePerShare (Annual)

Historical PE Range

Past 9 fiscal years · Front-end computed
Average
63.0x
9-yr mean
Median
29.0x
9-yr midpoint
Minimum
20.1x
Lowest year
Maximum
230.1x
Highest year
26.2x ← Now
20.1x
Min
Q1 · 25%29.0x
Median
Q3 · 75%230.1x
Max
Within Historical Range

At 26.17x, VRTX's current P/E is within its average historical range over the past 9 fiscal years.

44th percentileHigher than 4 of 9 historical fiscal year readings

Percentile calculated from annual fiscal year data points, not by trading day. Years where PE ≤ 0 or > 9,999 are excluded.

PE Ratio vs Peers

Biotechnology · 6 peers · Annual PE
CompanyMarket CapPE (Annual)vs AvgEPS (TTM)
Vertex Pharmaceuticals Incorporated
Vertex Pharmaceuticals IncorporatedYou
VRTX
$113.4B26.17x-0.1%$17.07
argenx SE
argenx SE
ARGX
$55.2B39.90x+52.3%$21.08
Bristol-Myers Squibb Company
Bristol-Myers Squibb Company
BMY
$116.9B15.61x-40.4%$3.46
CVS Health Corporation
CVS Health Corporation
CVS
$122.4B56.87x+117.1%$1.40
GSK plc
GSK plc
GSK
$103.6B6.45x-75.4%$5.64
HCA Healthcare, Inc.
HCA Healthcare, Inc.
HCA
$82.6B15.88x-39.4%$29.40
McKesson Corporation
McKesson Corporation
MCK
$93.2B22.46x-14.3%$38.53
Industry Average
6 peers with valid PE
26.19xbaseline

* N/A — Company is not profitable (TTM) · excluded from industry average · ▸ FMP /stock-peers + /ratios?limit=1 · priceToEarningsRatio

Annual PE Ratio History

Showing 10 of 20 years
Fiscal Year EndPE RatioEPS (TTM)YoY ChangePE vs Max
2025-12-31Latest
FY2025
29.32x$15.46
2024-12-31
FY2024
$-2.08
2023-12-31
FY2023
28.97x$14.05+30.1%
2022-12-31
FY2022
22.26x$12.97-7.9%
2021-12-31
FY2021
24.16x$9.09+6.7%
2020-12-31
FY2020
22.65x$10.44-52.6%
2019-12-31
FY2019
47.77x$4.58+137.7%
2018-12-31
FY2018
20.10x$8.25-85.8%
2017-12-31
FY2017
141.54x$1.06
2016-12-31
FY2016
$-0.46

▸ FMP /ratios?period=annual&limit=20 · priceToEarningsRatio + netIncomePerShare · Zero extra API

About PE Ratio & Methodology

The price-to-earnings (P/E) ratio for Vertex Pharmaceuticals Incorporated (VRTX) measures how much investors pay for each dollar of the company's trailing earnings. VRTX's current PE ratio of 26.17x is calculated by dividing its stock price of $446.83 by its TTM earnings per share of $17.07.

PE Ratio = Stock Price ÷ EPS (TTM)
= $446.83 ÷ $17.07 = 26.17x
TTMTrailing Twelve Months — sum of the most recent 4 quarterly EPS figures
Forward PEStock price ÷ analyst consensus EPS estimate for the next fiscal year
PEGPE ÷ earnings growth rate — values below 1.0 suggest growth may justify the premium
Figures tie to SEC 10-K/10-Q and FMP ratio endpoints where noted.

Frequently asked questions

VRTX pe ratio · 6 questions

VRTX's current PE ratio is 26.17x as of 2026-06-08, based on a stock price of $446.83 and TTM EPS of $17.07. Data sourced from Financial Modeling Prep via VRTX's SEC 10-K and 10-Q filings.

VRTX PE ratioWhat is VRTX PE ratioCurrent PE ratio of VRTXVRTX PE ratio today

Source: FMP · /ratios-ttm · /ratios annual · /analyst-estimates · /stock-peers · Vertex Pharmaceuticals Incorporated SEC 10-K & 10-Q filings · US GAAP · Updated: 2026-06-08