Companies: 10,795·Total market cap: $144.5T
Annexon, Inc.

Annexon, Inc.

ANNXNASDAQHealthcare● Active
$5.12
$-0.17(-3.21%)
Market Cap$612326661
P/E Ratio
52W High$7.18
52W Low$1.85

Annexon, Inc. (ANNX) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · ANNX · as of Sep 30, 2025

Ownership Breakdown

Institutions 84.78%
Insiders 0%
Public 22.38%

151

Institutional Holders

▲ 20 vs Q2

$309.26M

Total Inst. Value

▲ $70.53M vs Q2

119.60M

Shares Outstanding

freeFloat 107.16%

101.39M

13F Shares Held

▲ 1.69M vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

ANNX largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

FMR LLC

pharmaceutical preparations

11.08M7.47%

7.47%

$33.80BNov 13, 2025 4.61M

BLACKROCK, INC.

pharmaceutical preparations

7.90M5.33%

5.33%

$24.09BNov 12, 2025 63.4K

BVF INC/IL

pharmaceutical preparations

7.00M4.72%

4.72%

$21.35BNov 14, 2025— held

REDMILE GROUP, LLC

pharmaceutical preparations

6.30M4.25%

4.25%

$19.22BNov 14, 2025— held

VANGUARD GROUP INC

pharmaceutical preparations

5.84M3.93%

3.93%

$17.80BNov 7, 2025 469.1K

BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC

pharmaceutical preparations

5.25M3.54%

3.54%

$16.01BNov 14, 2025— held

BELLEVUE GROUP AG

pharmaceutical preparations

5.16M3.48%

3.48%

$15.73BNov 14, 2025— held

MORGAN STANLEY

pharmaceutical preparations

3.03M2.04%

2.04%

$9.24BMay 27, 2026 2.20M

MILLENNIUM MANAGEMENT LLC

pharmaceutical preparations

2.82M1.90%

1.90%

$8.61BNov 14, 2025 308.7K

WOODLINE PARTNERS LP

pharmaceutical preparations

2.64M1.78%

1.78%

$8.05BNov 14, 2025 1.58M

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBullish — more buying than selling

27

Increased

+9.86M shares

4

New Positions

first time holders

12

Decreased

−5.97M shares

0

Sold Out

fully exited

Net shares change (top 50)

+3.89M

+9.86M / −5.97M

Net new holders

+19

4 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

ANNX insider trading · insider activity

Source: SEC Form 4

Buy 44%Active transactions only56% Sell

Insiders have been net buyers of shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.

3

Buy transactions

0

Sell transactions

0.00

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

Satter Muneer A

director

May 28, 2026Purchase613,497$5.41$3.32M10.34MForm 4 ↗

Carson William H.

director

May 11, 2026Purchase8,000$5.78$46.2K78.4KForm 4 ↗

Carson William H.

director

Apr 10, 2026Purchase8,000$6.20$49.6K70.4KForm 4 ↗

Carson William H.

director

Mar 10, 2026Purchase8,000$5.67$45.4K62.4KForm 4 ↗

Dananberg Jamie

CHIEF MEDICAL OFFICER

Mar 2, 2026Sale5,820$5.43$31.6K123.6KForm 4 ↗

Overdorf Michael

EVP & CHIEF BUSINESS OFFICER

Mar 2, 2026Sale4,339$5.42$23.5K182.6KForm 4 ↗

Yednock Ted

EVP & CHIEF INNOVATION OFFICER

Mar 2, 2026Sale5,566$5.42$30.2K154.2KForm 4 ↗

ARTIS DEAN RICHARD

EVP & CHIEF SCIENTIFIC OFFICER

Mar 2, 2026Sale5,894$5.43$32.0K180.1KForm 4 ↗

Lew Jennifer

EVP & CHIEF FINANCIAL OFFICER

Mar 2, 2026Sale5,565$5.42$30.2K170.7KForm 4 ↗

Love Douglas

PRESIDENT AND CEO

Feb 19, 2026Award1,250,000$5.10$6.38M1.25MForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Annexon, Inc. (ANNX) is primarily owned by institutional investors, who hold approximately 84.8% of total shares outstanding. Company insiders own approximately 0.00%, while retail and public investors account for the remaining 22.38%.

The largest institutional shareholder of Annexon, Inc. is FMR LLC, holding approximately 11.08 million shares — equal to 7.47% of outstanding shares — as of September 30, 2025.

A total of 151 institutional investors currently hold ANNX stock, with a combined institutional value of approximately $309,260,931 as of the most recent 13F filing period.

Frequently asked questions

ANNX ownership

Annexon, Inc. (ANNX) is primarily owned by institutional investors, who hold approximately 84.8% of shares. The largest shareholder is FMR LLC with a 7.47% stake. Company insiders hold 0.00%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns ANNX stockANNX ownership structureSEC Form 13F institutional holdingsANNX float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025