Praxis Precision Medicines, Inc.
Praxis Precision Medicines, Inc. (PRAX) Stock Ownership
Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.
SEC 13F · FMP · PRAX · as of Mar 31, 2025
Ownership Breakdown
166
Institutional Holders
▼ 9 vs Q4
$889.63M
Total Inst. Value
▼ $782.09M vs Q4
21.14M
Shares Outstanding
freeFloat 109.45%
23.46M
13F Shares Held
▲ 1.74M vs Q4
Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.
Top Institutional Holders
PRAX largest shareholders · institutional ownership
Q1 2025 · SEC 13F
Showing top 10 holders
| Holder | Shares | % Owned | Weight | Value | Reported | Change |
|---|---|---|---|---|---|---|
CORMORANT ASSET MANAGEMENT, LP pharmaceutical preparations | 1.75M | 8.29% | 8.29% | $66.08B | May 15, 2025 | ▲ 51.8K |
ADAGE CAPITAL PARTNERS GP, L.L.C. pharmaceutical preparations | 1.74M | 8.28% | 8.28% | $66.00B | May 15, 2025 | ▲ 1.14M |
JANUS HENDERSON GROUP PLC pharmaceutical preparations | 1.51M | 7.15% | 7.15% | $58.35B | May 15, 2025 | ▲ 576.9K |
BLACKROCK, INC. pharmaceutical preparations | 1.42M | 6.73% | 6.73% | $53.66B | May 2, 2025 | ▼ 45.5K |
MORGAN STANLEY pharmaceutical preparations | 1.21M | 5.76% | 5.76% | $45.96B | May 15, 2025 | ▲ 50.1K |
SOLEUS CAPITAL MANAGEMENT, L.P. pharmaceutical preparations | 1.14M | 5.41% | 5.41% | $43.16B | May 15, 2025 | ▲ 896.2K |
PRICE T ROWE ASSOCIATES INC /MD/ pharmaceutical preparations | 1.10M | 5.20% | 5.20% | $41.50B | May 14, 2025 | ▼ 112.8K |
VANGUARD GROUP INC pharmaceutical preparations | 1.09M | 5.16% | 5.16% | $41.17B | May 9, 2025 | ▲ 23.4K |
VR ADVISER, LLC pharmaceutical preparations | 990.0K | 4.70% | 4.70% | $37.49B | May 15, 2025 | — held |
PERCEPTIVE ADVISORS LLC pharmaceutical preparations | 980.9K | 4.66% | 4.66% | $37.15B | Aug 6, 2025 | ▼ 348.8K |
Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).
Institutional Activity
Q1 2025 vs prior quarter
Q1 2025
25
Increased
+4.51M shares6
New Positions
first time holders16
Decreased
−1.60M shares0
Sold Out
fully exitedNet shares change (top 50)
+2.91M
+4.51M / −1.60M
Net new holders
+15
6 new / 0 exited
Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).
Insider Buying vs Selling
PRAX insider trading · insider activity
Source: SEC Form 4
10
Buy transactions
13
Sell transactions
0.77
Buy/Sell ratio
$0M
Total disposed
Recent Insider Transactions
Showing 10 most recent · Common Stock only
| Name · Role | Date | Type | Shares | Price | Value | After Trans. | Filing |
|---|---|---|---|---|---|---|---|
Mastrocola Lauren Principal Accounting Officer | May 14, 2026 | Award | 127 | $167.94 | $21.3K | 13.6K | Form 4 ↗ |
Nemiroff Alex General Counsel and Secretary | May 14, 2026 | Award | 78 | $167.94 | $13.1K | 26.0K | Form 4 ↗ |
Kelly Timothy Edwin Chief Financial Officer | May 14, 2026 | Award | 121 | $167.94 | $20.3K | 31.2K | Form 4 ↗ |
Sniecinski Megan Chief Operating Officer | May 14, 2026 | Award | 89 | $167.94 | $14.9K | 28.7K | Form 4 ↗ |
Souza Marcio Chief Executive Officer | May 14, 2026 | Award | 126 | $167.94 | $21.2K | 77.0K | Form 4 ↗ |
Arbuckle Stuart A director | Feb 6, 2026 | Award | 478 | — | — | 1.2K | Form 4 ↗ |
Arbuckle Stuart A director | Feb 6, 2026 | Award | 688 | — | — | 688 | Form 4 ↗ |
Arbuckle Stuart A director | Feb 6, 2026 | Award | 224 | $319.57 | $71.6K | 224 | Form 4 ↗ |
KINDLER JEFFREY B director | Feb 6, 2026 | Award | 478 | — | — | 1.2K | Form 4 ↗ |
KINDLER JEFFREY B director | Feb 6, 2026 | Award | 688 | — | — | 688 | Form 4 ↗ |
Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.
About institutional & insider ownership
Praxis Precision Medicines, Inc. (PRAX) is primarily owned by institutional investors, who hold approximately 100.0% of total shares outstanding. Company insiders own approximately 0.00%, while retail and public investors account for the remaining 9.45%.
The largest institutional shareholder of Praxis Precision Medicines, Inc. is CORMORANT ASSET MANAGEMENT, LP, holding approximately 1.75 million shares — equal to 8.29% of outstanding shares — as of March 31, 2025.
A total of 166 institutional investors currently hold PRAX stock, with a combined institutional value of approximately $889,629,046 as of the most recent 13F filing period.
Frequently asked questions
PRAX ownershipPraxis Precision Medicines, Inc. (PRAX) is primarily owned by institutional investors, who hold approximately 100.0% of shares. The largest shareholder is CORMORANT ASSET MANAGEMENT, LP with a 8.29% stake. Company insiders hold 0.00%. Data sourced from SEC Form 13F as of March 31, 2025.