Septerna, Inc.

SEPNNASDAQHealthcare● Active

$30.41

$-0.74(-2.38%)

Market Cap$1.4B

P/E Ratio—

52W High$32.63

52W Low$9.852

Avg Volume319K

Open$31.97

Beta2.38

Employees Ownership Insider Trades

Septerna, Inc. (SEPN) Number of Employees – History & Annual Headcount

Annual SEC headcount, year-over-year change, and per-employee efficiency — chart and full history below.

SEC EDGAR · FMP · SEPN · as of Mar 9, 2026

Latest filing snapshot

70,000

+0+0.00%vs prior year

Septerna, Inc. (SEPN) employee data is sourced from the annual SEC 10-K filing. As of 2025, full-time employees only. Global consolidated headcount. View SEC filing ↗

SEC 10-K·Period end: 2025-12-31·Full-time · Global

Total Employees

70,000

Change (1Y)

Growth % (1Y)

+0.00%

Revenue / Employee

$656

Net Income / Employee

$-698

Market Cap

$1.4B

SEPN Employee Count

2024 – 2025 · Annual · SEC filing

Source: SEC annual filings · Hover bar to view year data · Click to view original filing

Employees History

Filing Date	Period End	Employees	Change (1Y)	Growth (1Y)	SEC filing link
2026-03-09	2025-12-31	70,000	+0	+0.00%
2025-03-27	2024-12-31	70,000	—	—

▸ Source: SEC Annual Reports (Form 10-K / 20-F). Employee counts as of fiscal year end. Click the ↗ icon at the end of a row to open the original SEC filing in a new tab.

Related Companies — Employee Count

Biotechnology

#SymbolCompanyEmployeesMkt Cap

Fortrea Holdings Inc.

15,000$1.6B #3

MRVI

Maravai LifeSciences Holdings, Inc.

EyePoint Pharmaceuticals, Inc.

165$960M #6

BCAX

Bicara Therapeutics Inc. Common Stock

55$1.1B #7

ABUS

Arbutus Biopharma Corporation

44$838M

Source: /stock-peers + /profile.fullTimeEmployees · Click row → /employees · Sorted by headcount · SEPN peer comparison

About SEPN employees

SEPN Employees · Headcount

Septerna, Inc. (SEPN) employee data is sourced from the annual SEC 10-K filing. As of 2025, Septerna, Inc. had 70,000 full-time employees globally. Full-time employees only. Global consolidated headcount.

Septerna, Inc. employs 70,000 full-time employees as of the latest filing within the Biotechnology industry. Revenue per employee stands at $656, reflecting the company's operational efficiency.

Septerna, Inc.'s workforce increased by 0 (0.00%) in 2025 compared to the prior fiscal year. The historical trend reflects the company's expansion and contraction cycles.

Septerna, Inc.'s revenue per employee of $656 positions it among the notable performers in the Biotechnology sector for operational efficiency.

Revenue Financial statements Net income SEC filings Price history Forecast & ratings Ownership Earnings

Frequently Asked Questions

SEPN Employees · 5 questions

As of the latest SEC 10-K filing (2025), Septerna, Inc. had 70,000 full-time employees globally. This figure is sourced from the company's mandatory annual disclosure to the SEC.

Septerna, Inc. employee counthow many employees does Septerna, Inc. haveSEPN total employees 2025

▸ Data source: FMP /historical-employee-count · SEC EDGAR annual filings · As reported · Global consolidated headcount · As of 2026-03-09